醫學界視苯二氮䓬類藥物較以往常用的巴比妥鹽類藥物更好，因為後者的治療劑量和中毒劑量差距較少（即是稍微過量便容易中毒），且会形成较强的依赖性。過量服用地西泮較不容易引致死亡（不過仍然有人因服用地西泮過量而死亡），但如同時服用其它鎮靜劑或酒類則會增加危險。
Suicidal thoughts or steps is usually attributable to matters other than medicines. Should you have suicidal thoughts or actions, your healthcare provider may well check for other leads to.
Beri tahu dokter bahwa Anda sedang menggunakan diazepam sebelum menjalani pemeriksaan laboratorium tertentu atau operasi.
Before applying VALTOCO, convey to your healthcare supplier about all of your health care conditions, such as if you:
The ongoing use of benzodiazepines, together with diazepam, may bring about clinically considerable Actual physical dependence. The risks of dependence and withdrawal increase with lengthier treatment period and higher day-to-day dose. Abrupt discontinuation or immediate dosage reduction of diazepam soon after ongoing use could precipitate acute withdrawal reactions, that may be lifestyle-threatening.
Each individual VALTOCO only sprays 1 time and cannot be reused. Will not examination or key the nasal spray right before use.
“There is something empowering about getting a direct-use seizure medication that actually works for you, and I feel for me, this was a sign that something may be done about epilepsy, that we didn’t need to let it rule in excess of our lives any more.”
A second dose really should not be specified if there is worry about the individual’s respiration, they will need assist with their respiratory, or have Intense drowsiness.
Each and every dose of VALTOCO is offered in a person pack. Use the entire drugs in one pack for a whole dose.
Ventrikelsköljning bör utföras endast om mycket stor mängd bensodiazepiner intagits eller om medlet intagits i kombination med andra farliga preparat upp until en timme efter intaget.
It may be used in patients with open up-angle glaucoma that are receiving correct therapy, but is contraindicated in acute slender-angle glaucoma.
VALTOCO arrives able to use right out of your box No assembly essential Maintain various bins of VALTOCO sprayers handy—in the home, at click here function, or anyplace you regularly go—to be certain it is usually close by Retailer VALTOCO at area temperature (concerning sixty eight °F and 77 °F). No refrigeration is needed. You'll want to also maintain VALTOCO away from immediate gentle.
Metabolism: Diazepam is N-demethylated by CYP3A4 and 2C19 towards the Lively metabolite N-desmethyldiazepam, and is also hydroxylated by CYP3A4 on the active metabolite temazepam.
A reduce dose is recommended for patients with Serious respiratory insufficiency, as a consequence of the potential risk of respiratory melancholy.